{"id":6410,"date":"2024-10-13T17:18:58","date_gmt":"2024-10-13T14:18:58","guid":{"rendered":"https:\/\/www.klimik.org.tr\/koronavirus\/?p=6410"},"modified":"2024-10-15T17:20:39","modified_gmt":"2024-10-15T14:20:39","slug":"covid-19-kalp-krizi-felc-ve-olum-riskini-yillarca-artiriyor","status":"publish","type":"post","link":"https:\/\/www.klimik.org.tr\/koronavirus\/covid-19-kalp-krizi-felc-ve-olum-riskini-yillarca-artiriyor\/","title":{"rendered":"COVID-19, Kalp Krizi, Fel\u00e7 ve \u00d6l\u00fcm Riskini Y\u0131llarca Art\u0131r\u0131yor"},"content":{"rendered":"

\"\"Yeni yay\u0131mlanan bir ara\u015ft\u0131rma, COVID-19 ge\u00e7irmenin, kalp krizi, fel\u00e7 ve \u00f6l\u00fcm riskini iki kat\u0131na \u00e7\u0131kard\u0131\u011f\u0131n\u0131 g\u00f6sterdi. Ara\u015ft\u0131rman\u0131n ilgin\u00e7 bir bulgusu var: 0 kan grubundakilerde bu risk daha d\u00fc\u015f\u00fck.<\/strong><\/p>\n

Ara\u015ft\u0131rmay\u0131 Cleveland Klinik ile G\u00fcney Kaliforniya \u00dcniversitesi\u2019nden bilim insanlar\u0131 yapt\u0131. Kay\u0131tlar\u0131 iyi tutan Birle\u015fik Krall\u0131k verilerinden yararlan\u0131ld\u0131. \u015eubat-Aral\u0131k 2020 tarihleri aras\u0131nda, a\u015f\u0131lardan \u00f6nce COVID-19\u2019a yakalanan 10 bin 5 ki\u015fi ve infekte olmayan 217 bin 730 ki\u015fiye ait verilere bak\u0131ld\u0131.<\/p>\n

COVID-19 a\u015f\u0131lar\u0131n\u0131n kardiyovask\u00fcler hastal\u0131klar\u0131 ve buna ba\u011fl\u0131 \u00f6l\u00fcmleri art\u0131rd\u0131\u011f\u0131 iddias\u0131 pe\u015f pe\u015fe gelen ara\u015ft\u0131rmalarla yalanlan\u0131rken, bu \u00e7al\u0131\u015fma buna yol a\u00e7an\u0131n infeksiyonun ta kendisi oldu\u011funu s\u00f6yl\u00fcyor.<\/p>\n

Herhangi bir t\u00fcr COVID-19 infeksiyonu ge\u00e7irenlerin, te\u015fhisten sonraki \u00fc\u00e7 y\u0131la kadar kalp krizi, fel\u00e7 ve \u00f6l\u00fcm gibi b\u00fcy\u00fck bir kardiyak olay ge\u00e7irme olas\u0131l\u0131\u011f\u0131n\u0131n iki kat daha fazla oldu\u011fu bulundu. Risk, COVID-19 nedeniyle hastaneye kald\u0131r\u0131lan (a\u011f\u0131r ge\u00e7iren) hastalarda \u00f6nemli \u00f6l\u00e7\u00fcde daha y\u00fcksekti. Hatta infeksiyon, hastalar\u0131n daha \u00f6nce var olan bir kalp hastal\u0131\u011f\u0131ndan da etkiliydi.<\/p>\n

0 kan grubu daha az etkileniyor<\/strong><\/p>\n

\u0130leri genetik analizler kan grubu 0 olmayanlar\u0131n (A, B veya AB) \u00a0COVID-19 sonras\u0131 olumsuz bir kardiyovask\u00fcler olay ya\u015fama olas\u0131l\u0131\u011f\u0131n\u0131n daha y\u00fcksek oldu\u011funu da ortaya koydu. Kan grubuyla infeksiyon aras\u0131ndaki ili\u015fki, virus ile kan grubunu belirleyen genetik kodun aras\u0131nda olas\u0131 bir etkile\u015fim oldu\u011funu g\u00f6steriyor. Daha \u00f6nce yap\u0131lan ba\u015fka ara\u015ft\u0131rmalar, A, B ve AB kan grubuna sahip ki\u015filerin COVID-19\u2019a yakalanma riskinin daha y\u00fcksek oldu\u011funu da g\u00f6stermi\u015fti. Y\u00fcz ki\u015fiden yakla\u015f\u0131k 30\u2019u 0 kan grubuna sahip.<\/p>\n

\u00c7al\u0131\u015fma, Arteriosclerosis Thrombosis and Vascular Biology dergisinde yay\u0131mland\u0131.<\/p>\n

Son verileri yorumlayan ara\u015ft\u0131rmac\u0131lar, bir milyardan fazla insan\u0131n COVID-19 ge\u00e7irdi\u011fini, kalp krizi, fel\u00e7, \u00f6l\u00fcm riskinin \u00fc\u00e7 y\u0131l boyunca azalmad\u0131\u011f\u0131n\u0131 bu nedenle de kardiyovask\u00fcler hastal\u0131kta art\u0131\u015f beklendi\u011fini s\u00f6yledi.<\/p>\n

Kalp damar hastalar\u0131nda risk 12 kat art\u0131yor<\/h4>\n

Ara\u015ft\u0131rmay\u0131 de\u011ferlendiren T\u00fcrk Tabipleri Birli\u011fi Ba\u015fkan\u0131 ve Ankara \u00dcniversitesi T\u0131p Fak\u00fcltesi \u00f6\u011fretim \u00fcyesi, infeksiyon hastal\u0131klar\u0131 ve klinik mikrobiyoloji uzman\u0131 Prof. Dr. Alpay AZAP, \u015funlar\u0131 s\u00f6yledi: \u201cA\u015f\u0131lar kalp krizini art\u0131r\u0131yor diye su\u00e7lan\u0131rken biz hep bunu s\u00f6ylemeye \u00e7al\u0131\u015f\u0131yorduk. As\u0131l bunu yapan\u0131n COVID-19 hastal\u0131\u011f\u0131n\u0131n, virusunun kendisi oldu\u011funu anlatmaya \u00e7al\u0131\u015ft\u0131k. Bir kez daha anla\u015f\u0131ld\u0131 ki\u00a0 a\u015f\u0131lar bu riski azaltan koruyucu \u00f6nlemler asl\u0131nda.\u201d<\/p>\n

COVID-19 infeksiyonu s\u0131ras\u0131nda, ba\u015fka baz\u0131 infeksiyonlarda oldu\u011fu gibi ba\u011f\u0131\u015f\u0131kl\u0131k sistemi bazen a\u015f\u0131r\u0131 yan\u0131t veriyor. Bu s\u00fcre\u00e7 kan\u0131n p\u0131ht\u0131la\u015fmas\u0131n\u0131 kolayla\u015ft\u0131r\u0131yor. Dolay\u0131s\u0131yla zaten damar darl\u0131\u011f\u0131, damar kire\u00e7lenmeleri (ateroskleroz) olan hastalarda kalp krizi ve felce sebep olabiliyor.<\/p>\n

Azap, bu \u00e7al\u0131\u015fman\u0131n ilgin\u00e7 yan\u0131n\u0131n, infeksiyonun ge\u00e7irilmesinin \u00fczerinden \u00fc\u00e7 y\u0131l sonra bile kalp krizi ve fel\u00e7 etkisinin devam etmesi oldu\u011funu s\u00f6yledi.<\/p>\n

Buna daha \u00f6nce kalp ve damar hastal\u0131\u011f\u0131 bulunmayanlar da dahil. Daha \u00f6nce kalp damar hastal\u0131\u011f\u0131 tan\u0131s\u0131 olanlarda infeksiyon riski 12 kat artarken, olmayanlarda yedi kat art\u0131yor.<\/p>\n

Bunun sebebi hen\u00fcz \u00e7ok net de\u011fil. Ama virusun (SARS-CoV-2) v\u00fccudun ba\u011f\u0131\u015f\u0131kl\u0131k sistemini \u00e7ok uyard\u0131\u011f\u0131 ve akut d\u00f6nemde kan\u0131n p\u0131ht\u0131la\u015fmas\u0131n\u0131 kolayla\u015ft\u0131rd\u0131\u011f\u0131 biliniyor. Ayr\u0131ca damarlar\u0131n i\u00e7 y\u00fczeyini d\u00f6\u015feyen h\u00fccreleri de tutabiliyor. Hatta plaklar varsa oraya da yerle\u015febiliyor.<\/p>\n

Azap burada da ba\u011f\u0131\u015f\u0131kl\u0131k sistemini uyarmaya devam etti\u011fini anlatt\u0131: “Teorik olarak ba\u011f\u0131\u015f\u0131kl\u0131k sisteminin damar\u0131 d\u00f6\u015feyen h\u00fccrelerle, plaklarla u\u011fra\u015ft\u0131\u011f\u0131n\u0131 ve onlar\u0131n b\u00fcy\u00fcmesine ve t\u0131kan\u0131kl\u0131\u011fa sebep olabilece\u011fini zaten d\u00fc\u015f\u00fcn\u00fcyorduk. Bunu g\u00f6steren bir tak\u0131m \u00f6n bulgular da vard\u0131. \u2018Bunun klinik olarak bir sonucu da var m\u0131?\u2019 sorusunun yan\u0131t\u0131 bu \u00e7al\u0131\u015fmayla geldi. Dolay\u0131s\u0131yla SARS-CoV-2 bizim daha \u00f6nceden g\u00f6rd\u00fc\u011f\u00fcm\u00fcz solunum yolu viruslar\u0131ndan olduk\u00e7a farkl\u0131 oldu\u011funu her vesileyle ispatl\u0131yor.”<\/p>\n

Uzam\u0131\u015f COVID<\/strong><\/p>\n

COVID-19 infeksiyonunu ge\u00e7irenlerin %10\u2019unda uzam\u0131\u015f COVID geli\u015fiyor. \u0130nfeksiyon atlat\u0131lsa da uykusuzluk, konsantrasyon g\u00fc\u00e7l\u00fc\u011f\u00fc, nefesle ilgili sorunlara ba\u011fl\u0131 halsizlik, bitkinlik, yayg\u0131n kas a\u011fr\u0131lar\u0131na yol a\u00e7\u0131yor.<\/p>\n

Azap yeni ara\u015ft\u0131rman\u0131n virusun bir ba\u015fka etkisini net ortaya koydu\u011funu s\u00f6yledi: “Kalp damar sa\u011fl\u0131\u011f\u0131n\u0131 da etkileyen bir virus bu art\u0131k. COVID-19\u2019un b\u00fct\u00fcn komplikasyonlar\u0131 infeksiyonu a\u011f\u0131r ge\u00e7irenlerde daha belirgin ve s\u0131k.”<\/p>\n

Haber \u0130\u00e7in T\u0131klay\u0131n\u0131z<\/strong><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Yeni yay\u0131mlanan bir ara\u015ft\u0131rma, COVID-19 ge\u00e7irmenin, kalp krizi, fel\u00e7 ve \u00f6l\u00fcm riskini iki kat\u0131na \u00e7\u0131kard\u0131\u011f\u0131n\u0131 g\u00f6sterdi. Ara\u015ft\u0131rman\u0131n ilgin\u00e7 bir bulgusu var: 0 kan grubundakilerde bu risk daha d\u00fc\u015f\u00fck. Ara\u015ft\u0131rmay\u0131 Cleveland Klinik ile G\u00fcney Kaliforniya \u00dcniversitesi\u2019nden bilim insanlar\u0131 yapt\u0131. Kay\u0131tlar\u0131 iyi tutan Birle\u015fik Krall\u0131k verilerinden yararlan\u0131ld\u0131. \u015eubat-Aral\u0131k 2020 tarihleri aras\u0131nda, a\u015f\u0131lardan \u00f6nce COVID-19\u2019a yakalanan 10 bin 5 ki\u015fi ve infekte olmayan 217 bin 730 ki\u015fiye ait verilere bak\u0131ld\u0131. COVID-19 a\u015f\u0131lar\u0131n\u0131n kardiyovask\u00fcler hastal\u0131klar\u0131 ve buna ba\u011fl\u0131 \u00f6l\u00fcmleri art\u0131rd\u0131\u011f\u0131 iddias\u0131 pe\u015f pe\u015fe gelen ara\u015ft\u0131rmalarla yalanlan\u0131rken, bu \u00e7al\u0131\u015fma buna yol a\u00e7an\u0131n infeksiyonun ta kendisi oldu\u011funu s\u00f6yl\u00fcyor. Herhangi bir t\u00fcr COVID-19 infeksiyonu ge\u00e7irenlerin, te\u015fhisten sonraki […]<\/p>\n","protected":false},"author":4,"featured_media":6411,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[1],"tags":[],"_links":{"self":[{"href":"https:\/\/www.klimik.org.tr\/koronavirus\/wp-json\/wp\/v2\/posts\/6410"}],"collection":[{"href":"https:\/\/www.klimik.org.tr\/koronavirus\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.klimik.org.tr\/koronavirus\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.klimik.org.tr\/koronavirus\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/www.klimik.org.tr\/koronavirus\/wp-json\/wp\/v2\/comments?post=6410"}],"version-history":[{"count":1,"href":"https:\/\/www.klimik.org.tr\/koronavirus\/wp-json\/wp\/v2\/posts\/6410\/revisions"}],"predecessor-version":[{"id":6412,"href":"https:\/\/www.klimik.org.tr\/koronavirus\/wp-json\/wp\/v2\/posts\/6410\/revisions\/6412"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.klimik.org.tr\/koronavirus\/wp-json\/wp\/v2\/media\/6411"}],"wp:attachment":[{"href":"https:\/\/www.klimik.org.tr\/koronavirus\/wp-json\/wp\/v2\/media?parent=6410"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.klimik.org.tr\/koronavirus\/wp-json\/wp\/v2\/categories?post=6410"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.klimik.org.tr\/koronavirus\/wp-json\/wp\/v2\/tags?post=6410"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}