{"id":5250,"date":"2021-11-28T12:52:57","date_gmt":"2021-11-28T09:52:57","guid":{"rendered":"https:\/\/www.klimik.org.tr\/koronavirus\/?p=5250"},"modified":"2021-11-28T18:46:21","modified_gmt":"2021-11-28T15:46:21","slug":"klimik-derneginden-b-1-1-529-omikron-varyantiyla-ilgili-guncelleme","status":"publish","type":"post","link":"https:\/\/www.klimik.org.tr\/koronavirus\/klimik-derneginden-b-1-1-529-omikron-varyantiyla-ilgili-guncelleme\/","title":{"rendered":"KL\u0130M\u0130K Derne\u011fi’nden B.1.1.529 (Omikron) Varyant\u0131yla \u0130lgili G\u00fcncelleme"},"content":{"rendered":"

1.<\/strong><\/span> D\u00fcnya Sa\u011fl\u0131k \u00d6rg\u00fct\u00fc\u2019n\u00fcn (DS\u00d6) Virus Evrimi Teknik Dan\u0131\u015fma Grubu, G\u00fcney Afrika\u2019n\u0131n 24 Kas\u0131m\u2019da bildirdi\u011fi yeni varyant\u0131 (21K\/B.1.1.529), 26 Kas\u0131m\u2019da yapt\u0131\u011f\u0131 toplant\u0131yla kayg\u0131 verici varyant (VOC) olarak s\u0131n\u0131fland\u0131rm\u0131\u015f ve \u201comikron\u201d olarak adland\u0131rm\u0131\u015ft\u0131r.<\/p>\n

2.<\/strong><\/span> Omikron varyant\u0131n\u0131n nerede ortaya \u00e7\u0131kt\u0131\u011f\u0131 hen\u00fcz bilinmemektedir. Botswana ya da G\u00fcney Afrika\u2019da SARS-CoV-2 genomik izleme faaliyetlerinin g\u00fc\u00e7l\u00fc olmas\u0131ndan dolay\u0131 bu \u00fclkeler \u00f6n plana \u00e7\u0131km\u0131\u015f olabilir. \u0130lk kaynak herhangi bir Afrika \u00fclkesi olabilir.<\/p>\n

3.<\/span><\/strong> \u00dclkelerinin maruz kalaca\u011f\u0131 damgalanma ve k\u0131s\u0131tlamalara ra\u011fmen, varyantla ilgili edindikleri bilgileri neredeyse naklen payla\u015fan G\u00fcney Afrika y\u00f6netimi ve bilim insanlar\u0131 \u00f6rnek davran\u0131\u015f sergilemi\u015flerdir.<\/p>\n

4.<\/span><\/strong> Omikron varyant\u0131 28 Kas\u0131m itibariyle d\u00f6rt k\u0131tada saptanm\u0131\u015f durumdad\u0131r. Afrika k\u0131tas\u0131 d\u0131\u015f\u0131ndakiler, G\u00fcney Afrika seyahatinden d\u00f6nenler ya da onlar\u0131n temasl\u0131lar\u0131d\u0131r.<\/p>\n

5.<\/strong><\/span> DS\u00d6, s\u00fcrveyans ve genomik dizileme \u00e7al\u0131\u015fmalar\u0131n\u0131n art\u0131r\u0131lmas\u0131n\u0131, elde edilen verilerin payla\u015f\u0131lmas\u0131n\u0131, ilk vaka ve\/veya vaka k\u00fcmelenmelerinin kendilerine acilen bildirilmesini, virusun ve yol a\u00e7t\u0131\u011f\u0131 klinik tablonun, a\u015f\u0131lar\u0131n etkinlik durumunun bir an \u00f6nce a\u00e7\u0131\u011fa \u00e7\u0131kmas\u0131 i\u00e7in kapasitesi olanlar\u0131n katk\u0131 vermesini \u00f6nermektedir.<\/p>\n

6.<\/span><\/strong> Pek \u00e7ok \u00fclke ilk \u00f6nlem olarak G\u00fcney Afrika \u00fclkelerine seyahat k\u0131s\u0131tlamas\u0131n\u0131n yan\u0131 s\u0131ra \u00fclkelere giri\u015fte PCR testi ve karantina zorunlulu\u011funu tekrar uygulamaya sokma yoluna gitti. S\u00f6z konusu \u00f6nlemler varyant\u0131n yay\u0131l\u0131m\u0131n\u0131n yava\u015flat\u0131labilmesi i\u00e7in i\u015fe yarayabilir. Ancak uzun vadede bu \u00f6nlemlerin i\u015fe yaramad\u0131\u011f\u0131 di\u011fer varyantlarda g\u00f6r\u00fclm\u00fc\u015ft\u00fcr. \u00dclkeye giri\u015fi ve yay\u0131l\u0131m\u0131 geciktirebilmek i\u00e7in test ve s\u00fcrveyans kapasite ve say\u0131lar\u0131n\u0131n artt\u0131r\u0131lmas\u0131, \u00fclkeye giri\u015flerde \u00fclke ve a\u015f\u0131lanma durumuna g\u00f6re ay\u0131rt etmeksizin PCR testi uygulanmas\u0131 ve belli \u00fclkelerden gelenlere PCR testleri negatif \u00e7\u0131ksa bile karantina zorunlulu\u011fu getirilmesi gibi uygulamalar\u0131n en k\u00f6t\u00fc senaryo se\u00e7enekleri g\u00f6z \u00f6n\u00fcnde bulundurularak en az\u0131ndan yeni varyant\u0131n \u00f6zelliklerine ili\u015fkin veriler gelinceye dek s\u00fcrd\u00fcr\u00fclmesi ak\u0131lc\u0131 bir tutum olacakt\u0131r.<\/p>\n

7.<\/span><\/strong> \u015eu an i\u00e7in varyant\u0131n bula\u015f\u0131c\u0131l\u0131\u011f\u0131, neden oldu\u011fu klinik tablonun \u00f6zellikleri, ge\u00e7irilmi\u015f infeksiyon ve\/veya a\u015f\u0131lanma sonucu kazan\u0131lan ba\u011f\u0131\u015f\u0131kl\u0131\u011fa kar\u015f\u0131 diren\u00e7 ile ilgili olarak mutasyon profilinden yola \u00e7\u0131k\u0131larak yap\u0131lan tahminler d\u0131\u015f\u0131nda kesinle\u015fmi\u015f ve g\u00fcvenilir veriler bulunmamaktad\u0131r. Ancak, tahminler iyimser olunmas\u0131n\u0131 destekler nitelikte olmamakla birlikte, gereksiz ve zamans\u0131z bir panik havas\u0131na girmek i\u00e7in de bir neden yoktur.<\/p>\n

8.<\/span><\/strong> Bilinen korunma y\u00f6ntemleri hala ge\u00e7erlili\u011fini korumaktad\u0131r. A\u015f\u0131 ve antiviral etkili ajanlar konusunda olduk\u00e7a mesafe katedilmi\u015f durumdad\u0131r. Gerekti\u011finde bunlar h\u0131zla yeni varyant(lar)a uyarlanabilecektir. Ortak kan\u0131, mevcut a\u015f\u0131lar ya da ge\u00e7irilmi\u015f infeksiyonlar\u0131n sa\u011flad\u0131\u011f\u0131 ba\u011f\u0131\u015f\u0131kl\u0131\u011f\u0131n en az\u0131ndan a\u011f\u0131r hastal\u0131k ve \u00f6l\u00fcme kar\u015f\u0131 koruyuculuklar\u0131n\u0131 s\u00fcrd\u00fcrecekleri y\u00f6n\u00fcndedir.<\/p>\n

9.<\/span><\/strong> Varyant\u0131n bir\u00e7ok \u00fclkede saptanmas\u0131, varyant\u0131n \u015fimdilik g\u00f6r\u00fcnenin \u00f6tesinde bir yay\u0131l\u0131m d\u00fczeyine ula\u015fm\u0131\u015f olma olas\u0131l\u0131\u011f\u0131na i\u015faret ediyor olabilir. Bu nedenle vakalar\u0131n ilk g\u00f6r\u00fcld\u00fc\u011f\u00fc \u00fclkelere y\u00f6nelik tedbirlerin gereksiz yo\u011funluk ve uzunlukta uygulanmaya devam etmesi, bu \u00fclkelerin ekonomileri ve halk\u0131n\u0131n alt\u0131ndan kalkamayaca\u011f\u0131 zorluklara neden olabilir. Bu tarz \u00f6nlemlerden olumsuz etkilenecek \u00fclkelerin y\u00fck\u00fcn\u00fcn hafifletilmesi i\u00e7in uluslararas\u0131 dayan\u0131\u015fmaya\/yard\u0131mla\u015fmaya son derece ihtiya\u00e7 vard\u0131r. Aksi halde salg\u0131nlarla ilgili bilgilerin zaman\u0131nda payla\u015f\u0131lmas\u0131 sekteye u\u011frayacakt\u0131r.<\/p>\n

10.<\/span><\/strong> Afrika \u00fclkeleri a\u015f\u0131lanma oran\u0131lar\u0131n\u0131n en d\u00fc\u015f\u00fck oldu\u011fu \u00fclkelerdir. A\u015f\u0131lanma oranlar\u0131n\u0131n d\u00fc\u015f\u00fck kalmas\u0131n\u0131n sadece o \u00fclke ya da gruplar i\u00e7in de\u011fil, uluslararas\u0131 boyutta bir olumsuzlu\u011fa yol a\u00e7abilece\u011finin somut \u00f6rneklerinden birini ya\u015fad\u0131\u011f\u0131m\u0131z bu d\u00f6nemde, ba\u015fta geli\u015fmi\u015f \u00fclkeler olmak \u00fczere t\u00fcm uluslararas\u0131 kurum\/kurulu\u015flar\u0131n a\u015f\u0131 e\u015fitli\u011fini sa\u011flama konusunda \u00f6zveriyle i\u015f birli\u011fine gitmesi konusunda kaybedilecek zaman kalmam\u0131\u015ft\u0131r. A\u015f\u0131ya eri\u015fimin sa\u011fland\u0131\u011f\u0131 \u00fclkelerde bile a\u015f\u0131lanmaktan uzak duran kesimlerin de g\u00fcncel geli\u015fmeleri g\u00f6z \u00f6n\u00fcne alarak bir kez daha d\u00fc\u015f\u00fcnmelerinin zaman\u0131d\u0131r.<\/p>\n

\"\"
\nBNO News Omicron Tracker<\/em><\/a><\/p>\n

Klimik Derne\u011fi Y\u00f6netim Kurulu<\/strong><\/p>\n

Not:<\/strong> De\u011ferli katk\u0131lar\u0131 i\u00e7in Prof. Dr. Kenan Midilli\u2019ye te\u015fekk\u00fcrlerimizi sunar\u0131z.<\/em><\/p>\n

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1. D\u00fcnya Sa\u011fl\u0131k \u00d6rg\u00fct\u00fc\u2019n\u00fcn (DS\u00d6) Virus Evrimi Teknik Dan\u0131\u015fma Grubu, G\u00fcney Afrika\u2019n\u0131n 24 Kas\u0131m\u2019da bildirdi\u011fi yeni varyant\u0131 (21K\/B.1.1.529), 26 Kas\u0131m\u2019da yapt\u0131\u011f\u0131 toplant\u0131yla kayg\u0131 verici varyant (VOC) olarak s\u0131n\u0131fland\u0131rm\u0131\u015f ve \u201comikron\u201d olarak adland\u0131rm\u0131\u015ft\u0131r. 2. Omikron varyant\u0131n\u0131n nerede ortaya \u00e7\u0131kt\u0131\u011f\u0131 hen\u00fcz bilinmemektedir. Botswana ya da G\u00fcney Afrika\u2019da SARS-CoV-2 genomik izleme faaliyetlerinin g\u00fc\u00e7l\u00fc olmas\u0131ndan dolay\u0131 bu \u00fclkeler \u00f6n plana \u00e7\u0131km\u0131\u015f olabilir. \u0130lk kaynak herhangi bir Afrika \u00fclkesi olabilir. 3. \u00dclkelerinin maruz kalaca\u011f\u0131 damgalanma ve k\u0131s\u0131tlamalara ra\u011fmen, varyantla ilgili edindikleri bilgileri neredeyse naklen payla\u015fan G\u00fcney Afrika y\u00f6netimi ve bilim insanlar\u0131 \u00f6rnek davran\u0131\u015f sergilemi\u015flerdir. 4. Omikron varyant\u0131 28 Kas\u0131m itibariyle d\u00f6rt k\u0131tada saptanm\u0131\u015f durumdad\u0131r. Afrika […]<\/p>\n","protected":false},"author":4,"featured_media":5249,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[1],"tags":[],"_links":{"self":[{"href":"https:\/\/www.klimik.org.tr\/koronavirus\/wp-json\/wp\/v2\/posts\/5250"}],"collection":[{"href":"https:\/\/www.klimik.org.tr\/koronavirus\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.klimik.org.tr\/koronavirus\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.klimik.org.tr\/koronavirus\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/www.klimik.org.tr\/koronavirus\/wp-json\/wp\/v2\/comments?post=5250"}],"version-history":[{"count":8,"href":"https:\/\/www.klimik.org.tr\/koronavirus\/wp-json\/wp\/v2\/posts\/5250\/revisions"}],"predecessor-version":[{"id":5258,"href":"https:\/\/www.klimik.org.tr\/koronavirus\/wp-json\/wp\/v2\/posts\/5250\/revisions\/5258"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.klimik.org.tr\/koronavirus\/wp-json\/wp\/v2\/media\/5249"}],"wp:attachment":[{"href":"https:\/\/www.klimik.org.tr\/koronavirus\/wp-json\/wp\/v2\/media?parent=5250"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.klimik.org.tr\/koronavirus\/wp-json\/wp\/v2\/categories?post=5250"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.klimik.org.tr\/koronavirus\/wp-json\/wp\/v2\/tags?post=5250"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}