{"id":4840,"date":"2021-08-10T14:12:11","date_gmt":"2021-08-10T11:12:11","guid":{"rendered":"https:\/\/www.klimik.org.tr\/koronavirus\/?p=4840"},"modified":"2021-08-19T15:50:08","modified_gmt":"2021-08-19T12:50:08","slug":"favipiravir-ilaci-tedavide-etkisiz-karacigeri-yoruyor","status":"publish","type":"post","link":"https:\/\/www.klimik.org.tr\/koronavirus\/favipiravir-ilaci-tedavide-etkisiz-karacigeri-yoruyor\/","title":{"rendered":"Favipiravir \u0130lac\u0131 Tedavide Etkisiz, Karaci\u011feri Yoruyor!"},"content":{"rendered":"

\"\"T\u00fcrkiye COVID-19 vaka say\u0131s\u0131nda 25 binleri yeniden g\u00f6rd\u00fc, g\u00fcnl\u00fck vefat say\u0131s\u0131 ise 100\u2019\u00fc a\u015ft\u0131. Testi pozitif \u00e7\u0131kan her vatanda\u015fa Sa\u011fl\u0131k Bakanl\u0131\u011f\u0131\u2019n\u0131n tedavi paketi g\u00f6t\u00fcr\u00fcl\u00fcyor. Filyasyon ekiplerinin g\u00f6t\u00fcrd\u00fc\u011f\u00fc bu pakette yer alan favipiravir ilac\u0131n\u0131n tedaviye etkisi olmad\u0131\u011f\u0131 y\u00f6n\u00fcndeki tart\u0131\u015fmalara Ko\u00e7 \u00dcniversitesi\u2019nde Prof. Dr. \u00d6nder Erg\u00f6n\u00fcl liderli\u011finde bilim ekibi noktay\u0131 koydu. Be\u015f ay s\u00fcren ve sonu\u00e7lar\u0131 Avrupa Klinik Mikrobiyoloji ve \u0130nfeksiyon Hastal\u0131klar\u0131 dergisinde (Eur J Clin Microbiol Infect Dis) yay\u0131nlanan meta analiz \u00e7al\u0131\u015fmas\u0131, ilac\u0131n tedavide etkisinin olmad\u0131\u011f\u0131n\u0131 g\u00f6sterdi. \u201c\u0130la\u00e7 etkisiz. Bu ilac\u0131 almakla solunum deste\u011fini azaltm\u0131yorsunuz. Geli\u015fmi\u015f \u00fclkeler bir y\u0131ld\u0131r kullanm\u0131yor ama biz \u0131srar ediyoruz\u201d diyen KL\u0130M\u0130K Derne\u011fi Y\u00f6netim Kurulu \u00dcyesi Prof. Dr. Erg\u00f6n\u00fcl, ara\u015ft\u0131rman\u0131n sonu\u00e7lar\u0131n\u0131 de\u011ferlendirdi.<\/strong><\/p>\n

Vaka art\u0131\u015flar\u0131n\u0131 nas\u0131l de\u011ferlendiriyorsunuz?<\/strong><\/p>\n

Vakalar art\u0131yor ama daha hafif seyirli oldu\u011funu g\u00f6zlemliyoruz. Yine de a\u015f\u0131ya ra\u011fmen beklenenden daha a\u011f\u0131r seyreden vakalar da var. A\u015f\u0131s\u0131 olanlar\u0131n \u00e7o\u011funun \u00e7ift doz Sinovac yapt\u0131rd\u0131\u011f\u0131n\u0131 fark ettik.<\/p>\n

COVID-19 tedavisinde en ba\u015f\u0131ndan bu yana kullan\u0131lan favipiravir ile ilgili bir \u00e7al\u0131\u015fmay\u0131 tamamlad\u0131n\u0131z. Bize anlat\u0131r m\u0131s\u0131n\u0131z bu \u00e7al\u0131\u015fman\u0131n i\u00e7eri\u011fini?<\/strong><\/p>\n

Olduk\u00e7a g\u00fc\u00e7l\u00fc bir ara\u015ft\u0131rma ekibiyle bir meta analiz \u00e7al\u0131\u015fmas\u0131 y\u00fcr\u00fctt\u00fck. Ekiptekilerin alt\u0131 ki\u015fi, t\u0131p fak\u00fcltesi \u00f6\u011frencisi. T\u00fcrkiye, her zaman s\u00f6yledi\u011fimiz gibi insan kayna\u011f\u0131 a\u00e7\u0131s\u0131ndan \u00e7ok g\u00fc\u00e7l\u00fc. \u00c7ok parlak \u00f6\u011frencilerimiz var. Son \u00e7al\u0131\u015fmam\u0131z, favipiravirin COVID-19 tedavisinde etkinli\u011fi \u00fczerine yap\u0131lan ara\u015ft\u0131rmalar\u0131n meta analiziydi. Aral\u0131k ay\u0131nda ba\u015flad\u0131k, yakla\u015f\u0131k be\u015f ay s\u00fcrd\u00fc. Daha sonra bilimsel mecralarda yay\u0131nlanmas\u0131 da bu kadar zaman ald\u0131. Bu bizim favipiravir \u00fczerine yapt\u0131\u011f\u0131m\u0131z ikinci bilimsel \u00e7al\u0131\u015fma. \u00dc\u00e7\u00fcnc\u00fcs\u00fc de yolda. \u00c7al\u0131\u015fmam\u0131z\u0131n sonu\u00e7lar\u0131 d\u00fcnyada t\u00fcm hekimlerin kulland\u0131\u011f\u0131 rehberlere girecek. Biz bir sentez yapt\u0131k ve \u00e7al\u0131\u015fmam\u0131z\u0131n sonucunda favipiravir ilac\u0131n\u0131n COVID-19 \u00fczerinde hi\u00e7bir etkisi olmad\u0131\u011f\u0131n\u0131 g\u00f6rd\u00fck.<\/p>\n

En ba\u015f\u0131ndan bu yana binlerce hasta bu ilac\u0131 kulland\u0131. \u0130lac\u0131 kulland\u0131ktan sonra hastal\u0131\u011f\u0131n daha a\u011f\u0131r seyretti\u011fini s\u00f6yleyenler de oldu. \u0130lac\u0131n zararlar\u0131na dair bir sonu\u00e7 \u00e7\u0131kt\u0131 m\u0131?<\/strong><\/p>\n

\u0130la\u00e7, baz\u0131 ki\u015fileri olumsuz etkilemi\u015f olabilir. \u00c7\u00fcnk\u00fc bilindi\u011fi gibi sekiz ila\u00e7 al\u0131n\u0131yor. Bu da mide ve karaci\u011feri yoruyor. Enzimleri y\u00fckseltiyor. Bu ilac\u0131n etkisiz oldu\u011fu, yurtd\u0131\u015f\u0131nda da bir\u00e7ok ara\u015ft\u0131rma sonucunda ortaya konuldu. ABD, \u0130ngiltere, Almanya, Japonya dahil geli\u015fmi\u015f \u00fclkelerde uzun s\u00fcredir bu ila\u00e7 kullan\u0131lm\u0131yor. Biz de \u00e7al\u0131\u015fmam\u0131zda g\u00f6rd\u00fck ki bu ilac\u0131 ald\u0131\u011f\u0131n\u0131zda olumlu bir etki g\u00f6rm\u00fcyorsunuz; solunum sistemini destekleyen bir ila\u00e7 de\u011fil. \u0130nfeksiyonun ci\u011ferlere inmesini \u00f6nlemiyor. T\u0131pk\u0131 hidroksiklorokin gibi bir durum s\u00f6z konusu. Bu ilac\u0131 da hat\u0131rlarsan\u0131z \u201cetkili\u201d diye uzun s\u00fcre COVID-19 hastalar\u0131na verdik ama sonra hi\u00e7bir etkisi olmad\u0131\u011f\u0131n\u0131, hatta kalbi yordu\u011funu g\u00f6rd\u00fck.<\/p>\n

R\u00f6portaj\u0131n Devam\u0131 \u0130\u00e7in T\u0131klay\u0131n\u0131z\u00a0<\/strong><\/a><\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

T\u00fcrkiye COVID-19 vaka say\u0131s\u0131nda 25 binleri yeniden g\u00f6rd\u00fc, g\u00fcnl\u00fck vefat say\u0131s\u0131 ise 100\u2019\u00fc a\u015ft\u0131. Testi pozitif \u00e7\u0131kan her vatanda\u015fa Sa\u011fl\u0131k Bakanl\u0131\u011f\u0131\u2019n\u0131n tedavi paketi g\u00f6t\u00fcr\u00fcl\u00fcyor. Filyasyon ekiplerinin g\u00f6t\u00fcrd\u00fc\u011f\u00fc bu pakette yer alan favipiravir ilac\u0131n\u0131n tedaviye etkisi olmad\u0131\u011f\u0131 y\u00f6n\u00fcndeki tart\u0131\u015fmalara Ko\u00e7 \u00dcniversitesi\u2019nde Prof. Dr. \u00d6nder Erg\u00f6n\u00fcl liderli\u011finde bilim ekibi noktay\u0131 koydu. Be\u015f ay s\u00fcren ve sonu\u00e7lar\u0131 Avrupa Klinik Mikrobiyoloji ve \u0130nfeksiyon Hastal\u0131klar\u0131 dergisinde (Eur J Clin Microbiol Infect Dis) yay\u0131nlanan meta analiz \u00e7al\u0131\u015fmas\u0131, ilac\u0131n tedavide etkisinin olmad\u0131\u011f\u0131n\u0131 g\u00f6sterdi. \u201c\u0130la\u00e7 etkisiz. Bu ilac\u0131 almakla solunum deste\u011fini azaltm\u0131yorsunuz. Geli\u015fmi\u015f \u00fclkeler bir y\u0131ld\u0131r kullanm\u0131yor ama biz \u0131srar ediyoruz\u201d diyen KL\u0130M\u0130K Derne\u011fi Y\u00f6netim Kurulu \u00dcyesi Prof. […]<\/p>\n","protected":false},"author":4,"featured_media":4841,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[4],"tags":[],"_links":{"self":[{"href":"https:\/\/www.klimik.org.tr\/koronavirus\/wp-json\/wp\/v2\/posts\/4840"}],"collection":[{"href":"https:\/\/www.klimik.org.tr\/koronavirus\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.klimik.org.tr\/koronavirus\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.klimik.org.tr\/koronavirus\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/www.klimik.org.tr\/koronavirus\/wp-json\/wp\/v2\/comments?post=4840"}],"version-history":[{"count":1,"href":"https:\/\/www.klimik.org.tr\/koronavirus\/wp-json\/wp\/v2\/posts\/4840\/revisions"}],"predecessor-version":[{"id":4842,"href":"https:\/\/www.klimik.org.tr\/koronavirus\/wp-json\/wp\/v2\/posts\/4840\/revisions\/4842"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.klimik.org.tr\/koronavirus\/wp-json\/wp\/v2\/media\/4841"}],"wp:attachment":[{"href":"https:\/\/www.klimik.org.tr\/koronavirus\/wp-json\/wp\/v2\/media?parent=4840"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.klimik.org.tr\/koronavirus\/wp-json\/wp\/v2\/categories?post=4840"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.klimik.org.tr\/koronavirus\/wp-json\/wp\/v2\/tags?post=4840"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}